I suspect the Game will be waged more through intrigue, trickery and small skirmishing rather than large scale confrontations until Danaerys makes her trek over the ocean with dragons in tow. Everything will probably devolve into chaos until then---to the extent it hasn't alreasy---as Vary and Littlefinger pull strings and struggle against one another. The Others will take advantage of the chaos until Danaerys swoops in, literally, and unites the Seven Kingdoms again.
Hope I am wrong---she is the worst character ever and can't die fast enough as far as I am concerned. But you don't devote half a series to developing a character merely to kill her off in some inconsequential manner. Or so I fear....