The natural riposte for the B12 would be to add UConn -- then they've penetrated into ACC territory with a more valuable school than Louisville, while the ACC has penetrated western Kentucky, not really territory the B12 should covet.
So if Louisville to the ACC was damaging to the B12, it's only because UConn is unavailable -- ticketed for the B1G.
If the B12 were serious about maintaining their conference, they wouldn't have been hurt by the Louisville selection. Even if UConn is off the table, Cincy is as good an add as L'ville. But the B12 is not serious, and haven't been for a long time. That's why so many have left (Colorado, Nebraska, Missouri, A&M) and more will.