In basketball sure. Even Waylon has given up on basketball mattering.
Even in the looney world of message boards you can find anyone who thinks Duke is going anywhere but this thread.
Criteria for Expansion:
1) Markets
2) Markets
3) Markets
4) Football
4a) Basketball
I think the last two are relevant, but not drivers. Duke's problem is that it is a medium sized, elite, private school and the Big 10 wants big state schools. That said, it does bring a lot of national exposure. I don't think Duke to the Big 10 is likely, but it is not out of the question.
Duke is one of the top schools in the country, and its basketball program gives it a lot of credibility. It is one of a handful of schools that could effectively start their own conference if they wanted. If Duke and the remaining ACC schools decided to be a D1 Patriot League, Northwestern and Vanderbilt would listen.
If the Big 10 added UNC and UVa, I could see the Pac 12 taking a final look at Boise and BYU. Boise's academics are an issue, but it is a top football program, and that conference could use a boost athletically. Also, with the new playoff structure, especially if it goes to 8 or 16 teams, a program as good as Boise's could generate a ton of revenue for the conference with playoff berths. I could also see the Big 12, Big 10 and SEC saying that if they are all at 14, the Pac 12 needed to be at 14, and they had to take one for the team and take BYU and Boise, the only two schools outside the system that have a realistic shot of finishing Top 5. The only reason BYU is not in a major conference already is because of BYU. I think the Pac 12 likely just stands pat, but it could take one last look.